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The research directions that matter most for endometriosis include randomized controlled trials comparing GLP-1 medications to placebo in confirmed endometriosis patients, imaging studies assessing whether lesion size changes with GLP-1 treatment, biomarker studies identifying which patients are most likely to respond, and combination studies examining whether GLP-1 medications enhance the effectiveness of conventional hormonal treatments

No GI effects whatsoever, even mild ones, after escalation

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The overlapping receptor activation creates unpredictable effects and dramatically increases GI side effect risk